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当前位置:首页产品中心细胞因子及蛋白细胞因子PRP1223-5 µg重组人/小鼠/大鼠转化生长因子β1

重组人/小鼠/大鼠转化生长因子β1
产品简介:

Abbkine/亚科因重组人/小鼠/大鼠转化生长因子β1通过LAL法测定,每微克蛋白里内毒素含量<0.1 EU。

产品型号:PRP1223-5 µg

更新时间:2025-12-23

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产品介绍
品牌Abbkine/亚科因
TGF-β1 is a member of transforming growth factor β(TGF-β) family. Transforming growth factor-β polypeptide family is involved in the regulation of cell processes, including cell division, differentiation, movement, adhesion and death. TGF-β1 regulates many other growth factors positively and negatively. It inhibits the secretion and activity of many other cytokines, including interferon-γ, tumor necrosis factor-α and various interleukins. It can also reduce the expression level of cytokine receptor. TGF-β1 is a multifunctional protein that controls proliferation, differentiation and other functions in many cell types. It plays an important role in bone remodeling, because it is an effective stimulator of osteoblast bone formation, causing the chemotaxis, proliferation and differentiation of directional osteoblasts. Once cells lose their sensitivity to TGF-β1-mediated growth inhibition, autocrine TGF-β signal will promote tumor occurrence.

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